2,722 research outputs found

    Polyunsaturated fatty acid-derived lipid mediators and T cell function

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    Copyright © 2014 Nicolaou, Mauro, Urquhart and Marelli-Berg . This is an open- access article distributed under the terms of the Creative Commons Attribution License (CC BY) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms

    Polyunsaturated fatty acid-derived lipid mediators and T cell function

    Get PDF
    Copyright © 2014 Nicolaou, Mauro, Urquhart and Marelli-Berg . This is an open- access article distributed under the terms of the Creative Commons Attribution License (CC BY) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms

    Solubility behaviour, crystallisation kinetics and pour point : a comparison of linear alkane and triacyl glyceride solute/solvent mixtures

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    Mixtures of either a hydrocarbon wax in a hydrocarbon solvent or a long chain triacyl glyceride (TAG) in a TAG solvent show complex solubility boundary temperature hysteresis and precipitated crystal network formation leading to gelation. For these industrially-important systems, we show how the equilibrium solubility and its hysteresis, crystallisation kinetics and pour point temperature vary with solute concentration for representative examples of both hydrocarbon (n-tetracosane (C24) solute in n-heptane (C7) solvent) and TAG (tristearin (SSS) solute in tricaprylin (CCC) solvent) mixtures. The behaviour is modelled with good accuracy; thereby providing a useful aid to formulation and process optimisation

    The implementation and use of Ada on distributed systems with reliability requirements

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    The issues involved in the use of the programming language Ada on distributed systems are discussed. The effects of Ada programs on hardware failures such as loss of a processor are emphasized. It is shown that many Ada language elements are not well suited to this environment. Processor failure can easily lead to difficulties on those processors which remain. As an example, the calling task in a rendezvous may be suspended forever if the processor executing the serving task fails. A mechanism for detecting failure is proposed and changes to the Ada run time support system are suggested which avoid most of the difficulties. Ada program structures are defined which allow programs to reconfigure and continue to provide service following processor failure

    The RMS Survey: 6 cm continuum VLA observations towards candidate massive YSOs in the northern hemisphere

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    (Abridged) Context: The Red MSX Source (RMS) survey is an ongoing multi-wavelength observational programme designed to return a large, well-selected sample of massive young stellar objects (MYSOs). We have identified ∼\sim2000 MYSO candidates located throughout the Galaxy by comparing the colours of MSX and 2MASS point sources to those of known MYSOs. Aims: To identify the populations of UCHII regions and PNe within the sample and examine their Galactic distribution. Method: We have conducted high resolution radio continuum observations at 6 cm towards 659 MYSO candidates in the northern hemisphere (10\degr< l < 250\degr) using the VLA. In addition to these targeted observations we present archival data towards a further 315 RMS sources extracted from a previous VLA survey of the inner Galaxy. Results: We find radio emission towards 272 (∼\sim27% of the observed sample). Using results from other parts of our multi-wavelength survey we separate these RMS-radio associations into two distinct types of objects, classifying 51 as PNe and a further 208 as either compact or UC HII regions. Using this well selected sample of HII regions we estimate their Galactic scale height to be 0.6\degr. Conclusions: Using radio continuum and archival data we have identified 79 PNe and 391 HII regions within the northern RMS catalogue. We estimate the total fraction of contamination by PNe in the RMS sample is of order 10%. The sample of HII regions is probably the best representation to date of the Galactic population of HII regions as a whole.Comment: Accepted for publication in Astronomy and Astrophysics. 15 pages, 9 figures and 5 tables. Full versions of Tables 3, 4 and 5 and Figs. 2, 4 and 7 will only be available via CDS or the RMS website at http:/www.ast.leeds.ac.uk/cgi-bin/RMS/RMS_VLA_IMAGES.cg

    The implementation and use of Ada on distributed systems with high reliability requirements

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    The use and implementation of Ada in distributed environments in which reliability is the primary concern were investigated. In particular, the concept that a distributed system may be programmed entirely in Ada so that the individual tasks of the system are unconcerned with which processors they are executing on, and that failures may occur in the software or underlying hardware was examined. Progress is discussed for the following areas: continued development and testing of the fault-tolerant Ada testbed; development of suggested changes to Ada so that it might more easily cope with the failure of interest; and design of new approaches to fault-tolerant software in real-time systems, and integration of these ideas into Ada

    New ammonia masers towards NGC6334I

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    We report the detection of new ammonia masers in the non-metastable (8,6) and (11,9) transitions towards the massive star forming region NGC6334I. Observations were made with the ATCA interferometer and the emitting region appears unresolved in the 2.7" x 0.8" beam, with deconvolved sizes less than an arcsecond. We estimate peak brightness temperatures of 7.8 x 10^5 and 1.2 x 10^5 K for the (8,6) and (11,9) transitions, respectively. The masers appear coincident both spatially and in velocity with a previously detected ammonia (6,6) maser. We also suggest that emission in the (10,9), (9,9) and (7,6) transitions may also be masers, based on their narrow line widths and overlapping velocity ranges with the above masers, as observed with the single-dish Mopra radiotelescope

    Milliarcsecond structure of water maser emission in two young high-mass stellar objects associated with methanol masers

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    The 22.2 GHz water masers are often associated with the 6.7 GHz methanol masers but owing to the different excitation conditions they likely probe independent spatial and kinematic regions around the powering young massive star. We compared the emission of these two maser species on milliarcsecond scales to determine in which structures the masers arise and to test a disc-outflow scenario where the methanol emission arises in a circumstellar disc while the water emission comes from an outflow. We obtained high-angular and spectral resolution 22.2 GHz water maser observations of the two sources G31.581+00.077 and G33.641-00.228 using the EVN. In both objects the water maser spots form complex and filamentary structures of sizes 18-160 AU. The emission towards the source G31.581+00.077 comes from two distinct regions of which one is related to the methanol maser source of ring-like shape. In both targets the main axis of methanol distribution is orthogonal to the water maser distribution. Most of water masers appear to trace shocks on a working surface between an outflow/jet and a dense envelope. Some spots are possibly related to the disc-wind interface which is as close as 100-150 AU to the regions of methanol emission.Comment: 10 pages, accepted to Astronomy and Astrophysic
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